Col6a1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:208903 Pan TC, et al., A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16. J Biol Chem. 2014 Apr 11;289(15):10293-307
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5804159
Gene symbol:	Col6a1
Gene name:	collagen, type VI, alpha 1

Antibody:	collagen VI alpha1 antibody
Detection system:	Cy3

Results

5Ad ©

Specimen 5Ad: embryonic day 17.0 (more

)

Structure	Level	Pattern	Image	Note
TS25: limb	Present		5Ad	Fibrous expression pattern in dermis, skeletal muscle and around the ribs.

5Ae ©

Specimen 5Ae: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS25: limb	Strong		5Ae	Increased levels of expression in mutant limbs compared with wild-type.

5Af ©

Specimen 5Af: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS25: lung	Strong		5Af	Increased levels of expression in mutant limbs compared with wild-type.

5Ag ©

Specimen 5Ag: embryonic day 17.0 (more

)

Structure	Level	Pattern	Image	Note
TS25: limb	Present	Regionally restricted	5Ag	Fibrous expression pattern in dermis, skeletal muscle and around the ribs.

5Ah ©

Specimen 5Ah: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS25: limb	Present	Regionally restricted	5Ah	Authors report expression did not not exhibit the fibrous pattern, but instead appread amorphous.

5Ai ©

Specimen 5Ai: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS25: limb	Present	Regionally restricted	5Ai	Authors report expression did not not exhibit the fibrous pattern, but instead appread amorphous.

7A a1(VI) +/+ ©

Specimen 7A alpha1(VI) +/+: postnatal month 1 (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present		7A a1(VI) +/+

7A a1(VI) +/d16 ©

Specimen 7A alpha1(VI) +/d16: postnatal month 1; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Weak		7A a1(VI) +/d16	Expression somewhat decreased compared with wild-type muscle.

Specimen 7A alpha1(VI) d16/d16: postnatal month 1; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Weak		7A a1(VI) d16/d16	Expression somewhat decreased compared with wild-type muscle.

9_a1(VI) +/+ ©

Specimen 9 alpha1(VI) +/+: postnatal month 6 (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present		9_a1(VI) +/+

Specimen 9 alpha1(VI) +/d16: postnatal month 6; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Weak		9_a1(VI) +/d16	Expression somewhat decreased compared with wild-type muscle.

Specimen 9 alpha1(VI) d16/d16: postnatal month 6; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Weak		9_a1(VI) d16/d16	Expression somewhat decreased compared with wild-type muscle.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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