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Gene Expression Data
Assay Details
Assay
Reference: J:229524 Robert T, et al., The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800305
Gene symbol: Sycp1
Gene name: synaptonemal complex protein 1
Antibody: Anti-Scp1 (Ab-15090)
Detection system: Secondary antibody
Results
Specimen 5B +/+ Leptotene: postnatal day 30 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Absent 5B +/+ Leptotene Merge , 5B +/+ Leptotene Sycp1
Specimen 5B +/+ Zygotene: postnatal day 30 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present 5B +/+ Zygotene Sycp1 , 5B +/+ Zygotene Merge
Specimen 5B +/+ Pachytene: postnatal day 30 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present 5B +/+ Pachytene Merge , 5B +/+ Pachytene Sycp1
Specimen 5B -/- Leptotene: postnatal day 30; Top6blem2Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Absent 5B -/- Leptotene Merge , 5B -/- Leptotene Sycp1
Specimen 5B -/- Zygotene Like: postnatal day 30; Top6blem2Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present 5B -/- Zygotene like Merge upper , 5B -/- Zygotene like Sycp1 upper
Specimen 5B -/- Zygotene Like: postnatal day 30; Top6blem2Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present 5B -/- Zygotene like Sycp1 lower , 5B -/- Zygotene like Merge lower
Specimen S16A -/- Zygotene Like: postnatal month 8; Top6blem2Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present S16A Sycp1 , S16A Merge
Specimen S17B +/+ Leptotene: postnatal month 8 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Absent S17B_+/+ Leptotene Sycp1 , S17B_+/+ Leptotene merge
Specimen S17B +/+ Zygotene: postnatal month 8 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present S17B_+/+ Zygotene merge , S17B_+/+ Zygotene Sycp1
Specimen S17B +/+ Pachytene: postnatal month 8 (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present S17B_+/+ Pachytene merge , S17B_+/+ Pachytene Sycp1
Specimen S17B -/- Leptotene: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Absent S17B_-/- Leptotene merge , S17B_-/- Leptotene Sycp1
Specimen S17B -/- Zygo. Like: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present S17B_-/- Zygo. Like merge , S17B_-/- Zygo. Like Sycp1
Specimen S17B -/- Zygo Like: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: red - Sycp1; green - Sycp3 (assay MGI:5800309). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Present S17B_-/- Zygo Like Sycp1 , S17B_-/- Zygo Like merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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