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Gene Expression Data
Assay Details
Assay
Reference: J:123565 Hayakawa-Yano Y, et al., Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells. 2007 Jun;25(6):1410-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5795678
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Detection system: Secondary antibody
Results
Specimen 1K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 1K Expression is in the p3 domain.
TS20: spinal cord marginal layer Present 1K
Specimen 1O: embryonic day 12.5; Gab1tm1Thir/Gab1tm1Thir (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 1O Expression in this mutant is the same as in wild-type embryos.
TS20: spinal cord marginal layer Present 1O Expression in this mutant is the same as in wild-type embryos.
Specimen 3B: embryonic day 13.5 (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 3B Expression is ventral.
Specimen 3C: embryonic day 14.5; Gab1tm1Thir/Gab1tm1Thir (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS22: spinal cord marginal layer Present 3C
TS22: spinal cord ventricular layer Present 3C
Specimen 3H: embryonic day 13.5; Gab1tm1Thir/Gab1tm1Thir (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 3H Expression in this mutant is the same as in wild-type.
Specimen 3I: embryonic day 14.5; Gab1tm1Thir/Gab1tm1Thir (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS22: spinal cord marginal layer Present 3I Expression in this mutant is the same as in wild-type.
TS22: spinal cord ventricular layer Present 3I Expression in this mutant is the same as in wild-type.
Specimen 4E: embryonic day 13.5 (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS21: spinal cord marginal layer Present 4E Expression is ventral.
TS21: spinal cord ventricular layer Present 4E Expression is ventral.
Specimen 4F: embryonic day 13.5; Egfrtm1Mag/Egfrtm1Mag (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS21: spinal cord marginal layer Present 4F Expression in this mutant is the same as in wild-type embryos.
TS21: spinal cord ventricular layer Present 4F Expression in this mutant is the same as in wild-type embryos.
Specimen 4I: embryonic day 14.5 (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS22: spinal cord marginal layer Present 4I Expression is ventral.
TS22: spinal cord ventricular layer Present 4I Expression is ventral.
Specimen 4J: embryonic day 14.5; Egfrtm1Mag/Egfrtm1Mag (more )
Note: Double labeled: red - Nkx2-2; green - Olig2 (assay MGI:5795657).
Structure Level Pattern Image Note
TS22: spinal cord marginal layer Present 4J Expression in this mutant is the same as in wild-type.
TS22: spinal cord ventricular layer Present 4J Expression in this mutant is the same as in wild-type.
Specimen S1D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube Present S1D
Specimen S1I: embryonic day 11.0; Gab1tm1Thir/Gab1tm1Thir (more )
Structure Level Pattern Image Note
TS18: neural tube Present S1I Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory