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Gene Expression Data
Assay Details
Assay
Reference: J:151815 Ng L, et al., A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology. 2009 Apr;150(4):1952-60
Assay type: RNA in situ
MGI Accession ID: MGI:5792866
Gene symbol: Dio3
Gene name: deiodinase, iodothyronine type III
Probe: Dio3 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Present 2A left panel
TS24: cochlear ganglion Present 2A left panel
Specimen 2A right: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Present 2A right panel
TS24: greater epithelial ridge Present 2A right panel
TS24: cochlea epithelium Present Regionally restricted 2A right panel Expression is in the epithelium adjacent to the greater epithelial ridge.
TS24: cochlea Weak Regionally restricted 2A right panel Expression is in tissues surrounding the cochlear duct.
Specimen 2C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: stria vascularis Present 2C Dio3
TS27: vestibular membrane Present 2C Dio3
TS27: outer ear Present Regionally restricted 2C Dio3 Expression is in the tympanic border cells below the basilar membrane.
TS27: cochlea epithelium Present Regionally restricted 2C Dio3 Expression is in the greater epithelial ridge and sensory epithelium.
Specimen 2D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlea epithelium Present 2D Dio3 Expression is in the greater epithelial ridge.
Specimen 2E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 2E Dio3
Specimen 2F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present 2F Dio3
TS28: stria vascularis Present 2F Dio3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory