Gene Expression Data
Assay Details
Assay
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Reference:
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J:231881
Zeng L, et al., Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells. PLoS Genet. 2016 May;12(5):e1006055
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5790329
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Gene symbol:
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Ccnyl1
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Gene name:
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cyclin Y-like 1
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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Fixative was 0.2% glutaraldehyde, 1.5% formaldehyde.
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Results
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Specimen
2A:
postnatal week 5; Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1 +
(more )
Note: Right panel is a higher magnification of the boxed region.
Specimen
2A:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6N
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Mutant Allele(s):
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Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
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Age:
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postnatal week 5
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Sex:
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Female
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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Right panel is a higher magnification of the boxed region.
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Structure |
Level |
Pattern |
Image |
Note |
TS28: mammary gland |
Present |
Regionally restricted |
2A
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Expression is in the terminal end buds.
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Specimen
2B:
postnatal week 6; Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1 +
(more )
Note: Right panel is a higher magnification of the boxed region.
Specimen
2B:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6N
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Mutant Allele(s):
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Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
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Age:
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postnatal week 6
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Sex:
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Female
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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Right panel is a higher magnification of the boxed region.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: mammary gland |
Present |
Regionally restricted |
2B
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Expression is in the terminal end buds.
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Specimen
2C:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6N
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Mutant Allele(s):
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Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
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Age:
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postnatal week 5
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Sex:
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Female
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: mammary gland |
Present |
Regionally restricted |
2C
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Expression is in the terminal end buds in basal and surrounding stromal cells and rarely in the inner layer body cells.
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Specimen
S3B:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6N
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Mutant Allele(s):
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Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
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Age:
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postnatal week 8
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Sex:
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Female
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Paraffin
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