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Gene Expression Data
Assay Details
Assay
Reference: J:133600 Aoki M, et al., R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. Dev Growth Differ. 2008 Feb;50(2):85-95
Assay type: RNA in situ
MGI Accession ID: MGI:5788478
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe56
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4R: embryonic day 11.5; Rspo2tm1Hoka/Rspo2tm1Hoka (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Regionally restricted 4R Expression was absent in part of the AER and distal mesenchyme compared with wildtype hindlimbs.
TS19: footplate mesenchyme Present Regionally restricted 4R Expression was absent in part of the AER and distal mesenchyme compared with wildtype hindlimbs.
Specimen 4S: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 4S
TS19: footplate mesenchyme Present Regionally restricted 4S Expression in underlying mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory