Results
|
Specimen
1B/C:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
1B/C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
1B
,
1C
|
Expressed in the prospective somite S-1 and the posterior region during phase I.
|
Specimen
1H/I:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
1H/I:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
1I
,
1H
|
Expression in the posterior region and S-1 also moved anteriorly during phase II.
|
Specimen
1N/O:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
1N/O:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
1O
,
1N
|
Expression moved to the prospective somites S0 and S-2 region during phase III.
|
Specimen
1T/U:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Hes7tm1Kag/Hes7tm1Kag
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Specimen
2A/B/B'/C:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
2A/B/B'/C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2C
,
2A
,
2B'
,
2B
|
Expressions of Notch1 and Hes7 were clearly separated in the middle to anterior. In the posterior end, expressions of Notch1 and Hes7 were intermingled, and subsets of cells even coexpressed Notch1 and Hes7.
|
Specimen
2D/E/E'/F:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
2D/E/E'/F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2D
,
2F
,
2E
,
2E'
|
Expressions of Notch1 and Hes7 were clearly separated in the middle to anterior. In the posterior end, expressions of Notch1 and Hes7 were intermingled, and subsets of cells even coexpressed Notch1 and Hes7.
|
Specimen
2G/H/H'/I:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
Specimen
2G/H/H'/I:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2G
,
2I
,
2H
,
2H'
|
Expressions of Notch1 and Hes7 were clearly separated in the middle to anterior. In the posterior end, expressions of Notch1 and Hes7 were intermingled, and subsets of cells even coexpressed Notch1 and Hes7.
|
Specimen
2J/K/K'/L:
(close )
Genetic Background:
|
involves: 129S7/SvEvBrd
|
Mutant Allele(s):
|
Lfngtm1Rjo/Lfngtm1Rjo
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; green - Hes7 (assay MGI:5779930).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Scattered |
2K'
,
2J
,
2L
,
2K
|
In the posterior end, expressions of Notch1 and Hes7 were intermingled. Expression domains were not clearly segregated in either the S0 or S-1 region. Some cells even coexpressed Hes7 and Notch1.
|
Specimen
3A/B:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045).
Specimen
3A/B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
3A
,
3B
|
Expression moved from the middle to S-2 region during phase II, covered by the pMapk1/3 domain.
|
Specimen
3C/D:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045)
Specimen
3C/D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045)
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
3D
,
3C
|
Expression moved from the middle to S-2 region during phase III, covered by the pMapk1/3 domain.
|
Specimen
3E/F:
embryonic day 10.5
(more )
Note: Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045)
Specimen
3E/F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: purple - Notch1; cyan - phosphorylated Mapk1 (assay MGI:5779948) and Mapk3 (assay MGI:5780045)
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail unsegmented mesenchyme |
Present |
|
3F
,
3E
|
During phase I, when S-2 became S-1 after segmentation, pMapk1/3 expression was down-regulated and the whole Notch1 domain in S-1 was freed from pMapk1/3.
|
|