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Gene Expression Data
Assay Details
Assay
Reference: J:231044 Gage PJ, et al., Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7923-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5774853
Gene symbol: Mitf
Gene name: melanogenesis associated transcription factor
Antibody: anti-Mitf
Detection system: Secondary antibody
Results
Specimen 5J: embryonic day 12.5 (more )
Note: littermates were used for controls; their exact genotype was not detailed
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present 5J
Specimen 5K: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present 5K Expression is seen in the expected location; there are extreme morphological changes in the mutants.
Specimen 5L: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present 5L Expression is seen in the expected location; there are extreme morphological changes in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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