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Gene Expression Data
Assay Details
Assay
Reference: J:174212 Blaess S, et al., Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Dev. 2011;6:29
Assay type: RNA in situ
MGI Accession ID: MGI:5774798
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe118
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain floor plate Present 1A Expressed in a narrow medial domain overlying the notochord.
TS13: notochord Present 1A Expressed in a narrow medial domain overlying the notochord.
Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 1B/B' Expression expands laterally from the medial. There was some overlap between Shh and Gli1 expression at their domain boundaries (low expression).
Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 1C Expression expands laterally from the medial, but is downregulated medially.
Specimen 1D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 1D Expression expands laterally from the medial, but is downregulated medially.
Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 1E Expression expands laterally from the medial, but is downregulated medially.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory