Ascl2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:124707 Asanoma K, et al., HOP/NECC1, a novel regulator of mouse trophoblast differentiation. J Biol Chem. 2007 Aug 17;282(33):24065-74
Assay type:	RNA in situ
MGI Accession ID:	MGI:5766474
Gene symbol:	Ascl2
Gene name:	achaete-scute family bHLH transcription factor 2

Probe:	Mash2 probe3
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 2E +/+: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS28: placenta	Present		2E Mash2 HOP/NECC1+/+

Specimen 2E -/-: embryonic day 11.5; Hopx^tm1Eno/Hopx^tm1Eno (more

)

Structure	Level	Pattern	Image	Note
TS19: trophoblast giant cell	Present		2E Mash2 HOP/NECC1-/-	Expression was detected in the Prl3d1-positive cells.

Specimen 2F +/+: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: labyrinthine zone	Present		2F Mash2 HOP/NECC1+/+	Expression was detected in precursor cells.

Specimen 2F -/-: embryonic day 10.5; Hopx^tm1Eno/Hopx^tm1Eno (more

)

Structure	Level	Pattern	Image	Note
TS17: labyrinthine zone	Weak		2F Mash2 HOP/NECC1-/-	There was a marked reduction of the expressing cell population in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/28/2024 MGI 6.13