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Gene Expression Data
Assay Details
Assay
Reference: J:39208 Sosa-Pineda B, et al., The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature. 1997 Mar 27;386(6623):399-402
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5755862
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-IPF1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Authors did not specify if this antibody or anti-PDX1 antibody ( MGI:5755865) in this assay.
Results
Specimen 3c: embryonic day 10.5 (more )
Note: vibratome section.
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present 3c

Specimen 3f: embryonic day 10.5; Pax4tm1Pgr/Pax4tm1Pgr (more )
Note: vibratome section.
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present 3f Expression in this mutant is the same as in wild-type.

Specimen 4a: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 4a Expression is in beta cells.

Specimen 4b: postnatal newborn; Pax4tm1Pgr/Pax4tm1Pgr (more )
Structure Level Pattern Image Note
TS27: islets of Langerhans Absent 4b


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory