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Gene Expression Data
Assay Details
Assay
Reference: J:166923 Wang B, et al., Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B. Hum Mol Genet. 2011 Jan 15;20(2):271-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5755263
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5A No positive cells were found in distal limb mesenchyme within 200 um from the apical ectodermal ridge.

Specimen 5B: embryonic day 11.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5B There were positive cells found in distal limb mesenchyme within 200 um from the apical ectodermal ridge.

Specimen not shown: embryonic day 11.5; Vangl2Lp/Vangl2Lp, Wnt5atm1Amc/Wnt5a+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present There were positive cells found in distal limb mesenchyme within 200 um from the apical ectodermal ridge.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory