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Gene Expression Data
Assay Details
Assay
Reference: J:195176 Driver EC, et al., The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea. Dev Biol. 2013 Apr 1;376(1):86-98
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5754610
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Antibody: anti-ATOH1
Results
Specimen 7A: embryonic day 14.0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS22: cochlea Present Single cells 7A Expression is in hair cell nuclei.
Specimen 7B: embryonic day 16.0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS24: cochlea epithelium Strong Single cells 7B Expression is in hair cell nuclei at the apex of the cochlea.
Specimen 7C: embryonic day 16.0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS24: cochlea Strong Single cells 7C Expression is in hair cell nuclei at the base of the cochlea.
Specimen 7D: postnatal day 0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS27: cochlea Strong Single cells 7D Expression is in hair cells at the apex and is nearly undetectable at the base of the cochlea.
Specimen 7E: postnatal day 0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS27: cochlea Present Single cells 7E Expression is in hair cells. Staining is stronger in the outer hair cells.
Specimen 7F: postnatal day 0 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS27: cochlea Present Single cells 7F Expression is in hair cells.
Specimen 7I: postnatal day 5 (more )
Note: Double labeled: red - Atoh1; green - Myo6 (assay MGI:5754609).
Structure Level Pattern Image Note
TS28: cochlea Absent 7I
Specimen 7J,K: embryonic day 16.0 (more )
Note: Triple labeled: red - Atoh1; blue - Myo6 (assay MGI:5754609); green - Sox2 (assay MGI:5754612).
Structure Level Pattern Image Note
TS24: cochlea Present Single cells 7K , 7J Expression is in hair cells.
Specimen 7L: embryonic day 16.0; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Note: Triple labeled: red - Atoh1; blue - Myo6 (assay MGI:5754609); green - Sox2 (assay MGI:5754612).
Structure Level Pattern Image Note
TS24: cochlea Absent 7L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory