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Gene Expression Data
Assay Details
Assay
Reference: J:163968 Liu X, et al., Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation. 2009 Jan 20;119(2):261-8
Assay type: Western blot
MGI Accession ID: MGI:5754556
Gene symbol: Tpm1
Gene name: tropomyosin 1, alpha
Antibody: anti-tropomyosin (sarcomeric)
Detection system: Secondary antibody
Assay notes: Protein was subjected to isoelectric focusing electrophoresis followed by Western blotting.
Results Image: 6B
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex
+/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Speg+Not Specified
+/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Speg+Not Specified
-/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Spegtm1MkapNot Specified
+/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Speg+Not Specified
+/+ E16.5 TS24: heart Present Not Specified Not Specified
+/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Speg+Not Specified
-/- E16.5 TS24: heart Present either: B6.129S2-Spegtm1Mkap or (involves: 129S2/SvPas * C57BL/6) Spegtm1Mkap/Spegtm1MkapNot Specified
+/+ -PPase Treated sample: no data stored
+/+ +PPase Treated sample: no data stored
Notes:
(a) Protein extracts from the hearts of homozygous mutant embryos demonstrated a different isoelectric focus (lower bands) than hearts of wild-type and heterozygous embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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