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Gene Expression Data
Assay Details
Assay
Reference: J:70346 Kim AS, et al., Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS. J Neurosci. 2001 Mar 1;21(5):RC132
Assay type: RNA in situ
MGI Accession ID: MGI:5752590
Gene symbol: Sfrp2
Gene name: secreted frizzled-related protein 2
Probe: Sfrp2 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Non-Uniform 1A Weak expression was found throughout the forebrain. Higher expression in the diencephalon had a posterior boundary in zona limitans intrathalamica, a rostral p4/p5 limit, and dorsally in the eminentia thalami as it entered the telencephalon.
TS17: diencephalon Present Regionally restricted 1A There was a sharply demarcated region of higher expression in a restricted domain in the diencephalon.
TS17: telencephalon Present Regionally restricted 1A Expression was detected in the caudal telencephalon.

Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present Non-Uniform 1B The E10.5 pattern of expression was maintained at E14.5.
TS22: diencephalon Present Regionally restricted 1B Expression was detected in the eminentia thalami.
TS22: telencephalon Present Regionally restricted 1B Expression was detected in the ventral pallium.

Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present Non-Uniform 1C Expression in p5 was more prominent than at E10.5. Expression was detected in the developing pallial-sub-pallial boundary.
TS22: diencephalon Present 1C
TS22: caudal ganglionic eminence Present Regionally restricted 1C Expression was detected in a small domain flanking the caudal ganglionic eminence.

Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: caudal ganglionic eminence Present 1D

Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: amygdala Present Scattered 1E
TS24: neocortex Present Scattered 1E
TS24: diencephalon Present 1E
TS24: caudal ganglionic eminence Present 1E

Specimen not shown: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: diencephalon Absent

Specimen 1F: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: amygdala Present Scattered 1F
TS28: neocortex Present Scattered 1F
TS28: piriform cortex Present Scattered 1F
TS28: nucleus of diagonal band Present Regionally restricted 1F Expression was detected in the vertical limb of the diagonal band.

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 2B , 2D Expression was detected in the pallial side of the pallial-sub-pallial boundary, in the ventricular zone of the ventral pallium. Expression overlaps with Pax6, and abuts the Dlx2 expression.

Specimen 3A: embryonic day 13.5; Pax6Sey-Neu/Pax6+ (more )
Structure Level Pattern Image Note
TS21: diencephalon Present 3A
TS21: telencephalon Present Regionally restricted 3A Expression was detected in the ventral pallium of the pallial-sub-pallial boundary.

Specimen 3B: embryonic day 13.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS21: diencephalon Absent 3B
TS21: telencephalon Absent 3B Expression was undetectable in the ventral pallium.

Specimen not shown E13.5 Dlx1/Dlx2 mutant: embryonic day 13.5; Dlx1tm1Jlr/Dlx1tm1Jlr, Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Expression in the mutant was unaffected.
TS21: telencephalon Present Regionally restricted Expression in the mutant ventral pallium was unaffected.

Specimen not shown E14.5 Dlx1/Dlx2 mutant: embryonic day 14.5; Dlx1tm1Jlr/Dlx1tm1Jlr, Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Expression in the mutant was unaffected.
TS22: telencephalon Present Regionally restricted Expression in the mutant ventral pallium was unaffected.

Specimen not shown E16.5 Dlx1/Dlx2 mutant: embryonic day 16.5; Dlx1tm1Jlr/Dlx1tm1Jlr, Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Structure Level Pattern Image Note
TS24: diencephalon Present Expression in the mutant was unaffected.
TS24: telencephalon Present Regionally restricted Expression in the mutant ventral pallium was unaffected.

Specimen 4A: embryonic day 10.5; Pax6Sey-Neu/Pax6+ (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4A Expression was detected in the intermediate and ventral zones of the spinal cord.
TS17: dorsal root ganglion Absent 4A

Specimen 4B: embryonic day 10.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS17: future spinal cord Weak 4B Expression was greatly reduced in the mutant.
TS17: dorsal root ganglion Absent 4B


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory