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Gene Expression Data
Assay Details
Assay
Reference: J:35540 Bouillet P, et al., A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid. Mech Dev. 1996 Aug;58(1-2):141-52
Assay type: RNA in situ
MGI Accession ID: MGI:5752292
Gene symbol: Wnt8a
Gene name: wingless-type MMTV integration site family, member 8A
Probe: Stra11 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A (left): embryonic day 7.0 (more )
Note: Midstreak stage.
Structure Level Pattern Image Note
TS10: embryo Present Regionally restricted 4A (left) Expression in a limited posterior region of the epiblast.
Specimen 4A (middle): embryonic day 7.25 (more )
Note: Late streak stage.
Structure Level Pattern Image Note
TS10: embryo ectoderm Present Regionally restricted 4A (middle) Specific expression in a wide posterior region of embryonic ectoderm. Expression extended from distal tip of conceptus to posterior limit of embryo.
TS10: extraembryonic component Absent 4A (middle) No expression in extraembryonic regions.
Specimen 4A (right): embryonic day 7.5 (more )
Note: Neural plate stage.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present Regionally restricted 4A (right) Specific expression in a wide posterior region of embryonic ectoderm. Expression extended from distal tip of conceptus to posterior limit of embryo.
TS11: extraembryonic component Absent 4A (right) No expression in extraembryonic regions.
Specimen 4B (mWnt-8): embryonic day 7.75 (more )
Note: Early headfold stage.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present Regionally restricted 4B (mWnt-8) Specific expression in wide posterior region of embryonic ectoderm. Expression extended from distal tip of conceptus to posterior limit of embryo, and toward lateral and rostral regions of ectoderm.
TS11: embryo mesoderm Present Regionally restricted 4B (mWnt-8) Expression in ectoderm and mesoderm adjacent to primitive streak.
TS11: primitive streak Present Regionally restricted 4B (mWnt-8) Expression in ectoderm and mesoderm adjacent to primitive streak.
TS11: extraembryonic component Absent 4B (mWnt-8) No expression in extraembryonic regions.
Specimen 4C: embryonic day 8.0 (more )
Note: Late headfold stage.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 4C Sharp rostral boundary of expression at base of developing headfolds.
TS11: extraembryonic component Absent 4C No expression in allantois or other extraembryonic regions.
Specimen 4D: embryonic day 8.0 (more )
Note: Late headfold stage.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 4D Well defined lateral boundaries of expression.
Specimen 4E (mWnt-8): embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: embryo Absent 4E (mWnt-8)
Specimen 4F: embryonic day 8.0 (more )
Note: 5 somite pairs.
Structure Level Pattern Image Note
TS12: rhombomere Present 4F Restricted expression in the prospective fourth rhombomere.
TS12: neural ectoderm Present Regionally restricted 4F Expression in posterior regions of neurectoderm.
Specimen not shown: embryonic day 8.5 (more )
Note: Embryo in the process of turning.
Structure Level Pattern Image Note
TS13: rhombomere 4 Weak Authors report weak expression unambiguously restricted to rhombomere 4.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory