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Gene Expression Data
Assay Details
Assay
Reference: J:202865 Yang T, et al., Prickle1 stunts limb growth through alteration of cell polarity and gene expression. Dev Dyn. 2013 Nov;242(11):1293-306
Assay type: RNA in situ
MGI Accession ID: MGI:5751409
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf-8b cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 5C Expression in the apical ectodermal ridge.
TS20: forelimb interdigital region Ambiguous 5C Authors state expression is downregulated in the interdigital space in the wild type.
Specimen 5D: embryonic day 12.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 5D Expression in the apical ectodermal ridge.
TS20: forelimb interdigital region Present Regionally restricted 5D
Specimen 6C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 6C
Specimen 6D: embryonic day 11.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 6D No obvious difference in expression between wild type and mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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