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Gene Expression Data
Assay Details
Assay
Reference: J:226416 Zhang J, et al., Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice. Hum Mol Genet. 2015 Nov 1;24(21):6174-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5750159
Gene symbol: Loxl3
Gene name: lysyl oxidase-like 3
Antibody: anti-LOXL3
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 7A,C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 7C , 7A
TS22: tongue Present 7C , 7A
Specimen 7D,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Present 7D , 7F
TS22: intervertebral disc Present 7D , 7F
TS22: lung Present 7D , 7F
TS22: spinal cord meninges Present 7D , 7F
TS22: vertebral cartilage condensation Present 7D , 7F Expression in cartilage primordia.
TS22: connective tissue Present Regionally restricted 7F , 7D Expression in anterior and posterior longitudinal ligaments.
Specimen 7G,I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cornea Weak 7G , 7I
TS26: sclera Weak 7G , 7I
TS26: eyelid Strong Regionally restricted 7I , 7G Strong expression in skin of eyelid.
Specimen S4 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Present S4_E12.5
Specimen S4 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present S4_E13.5
Specimen S4 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present S4_E14.5
Specimen S4 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: palatal shelf mesenchyme Present S4_E15.5
Specimen S4 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: palate mesenchyme Present S4_E16.5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory