Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:105752
Wang Y, et al., The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci. 2006 Feb 22;26(8):2147-56
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5749547
|
|
Gene symbol:
|
Fzd6
|
|
Gene name:
|
frizzled class receptor 6
|
|
|
Results
|
Specimen
5F WT:
embryonic day 18.0
(more  )
Note: Double labeled with phalloidin (red). Flat mount.
Specimen
5F WT:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mount.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Present |
Regionally restricted |
5F WT
|
Expression is in hair cells and supporting cells.
|
Specimen
5F Fz3-/-:
embryonic day 18.0; Fzd3tm1Nat/ Fzd3tm1Nat
(more )
Note: Double labeled with phalloidin (red). Flat mount.
Specimen
5F Fz3-/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Fzd3tm1Nat/Fzd3tm1Nat
|
|
Age:
|
embryonic day 18.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mount.
|
Specimen
5F Fz6-/-:
postnatal day 2; Fzd6tm1Nat/ Fzd6tm1Nat
(more )
Note: Double labeled with phalloidin (red). Flat mount.
Specimen
5F Fz6-/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Fzd6tm1Nat/Fzd6tm1Nat
|
|
Age:
|
postnatal day 2
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mount.
|
Specimen
5F Lp/Lp:
embryonic day 18.0; Vangl2Lp/ Vangl2Lp
(more )
Note: Double labeled with phalloidin (red). Flat mount.
Specimen
5F Lp/Lp:
(close )
|
Genetic Background:
|
involves: LPT/LeJ
|
|
Mutant Allele(s):
|
Vangl2Lp/Vangl2Lp
|
|
Age:
|
embryonic day 18.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mount.
|
Specimen
6B utricle Lp/Lp:
embryonic day 18.5; Vangl2Lp/ Vangl2Lp
(more )
Note: Double labeled with phalloidin (red). Flat mounts.
Specimen
6B utricle Lp/Lp:
(close )
|
Genetic Background:
|
involves: LPT/LeJ
|
|
Mutant Allele(s):
|
Vangl2Lp/Vangl2Lp
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mounts.
|
Specimen
6B utricle Fz3-/-:
embryonic day 18.5; Fzd3tm1Nat/ Fzd3tm1Nat
(more )
Note: Double labeled with phalloidin (red). Flat mounts.
Specimen
6B utricle Fz3-/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Fzd3tm1Nat/Fzd3tm1Nat
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mounts.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: utricle |
Present |
Regionally restricted |
6B utricle Fz3-/-
,
6B utricle merge
|
Expression is localized to those sides of the polygonal epithelial cells that lie approximately at right angles to the hair bundle orientation.
|
Specimen
6B crista Lp/Lp:
embryonic day 18.5; Vangl2Lp/ Vangl2Lp
(more )
Note: Double labeled with phalloidin (red). Flat mounts.
Specimen
6B crista Lp/Lp:
(close )
|
Genetic Background:
|
involves: LPT/LeJ
|
|
Mutant Allele(s):
|
Vangl2Lp/Vangl2Lp
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mounts.
|
Specimen
6B crista Fz3-/-:
embryonic day 18.5; Fzd3tm1Nat/ Fzd3tm1Nat
(more )
Note: Double labeled with phalloidin (red). Flat mounts.
Specimen
6B crista Fz3-/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Fzd3tm1Nat/Fzd3tm1Nat
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red). Flat mounts.
|
Specimen
not shown WT:
embryonic day 18.5
(more )
Specimen
not shown WT:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: crista ampullaris |
Present |
Regionally restricted |
|
Expression is at the plasma membrane in hair cells and supporting cells.
|
| TS26: utricle |
Present |
Regionally restricted |
|
Expression is at the plasma membrane in hair cells and supporting cells.
|
Specimen
7A,C:
postnatal day 0
(more )
Note: Double labeled with phalloidin (red).
Specimen
7A,C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Present |
Regionally restricted |
7A
,
7C
|
Expression is near the apical surface of the sensory epithelia.
|
Specimen
7B,D:
postnatal day 0; Fzd6tm1Nat/ Fzd6tm1Nat
(more )
Note: Double labeled with phalloidin (red).
Specimen
7B,D:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Fzd6tm1Nat/Fzd6tm1Nat
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Note:
|
Double labeled with phalloidin (red).
|
|
Analysis Tools