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Gene Expression Data
Assay Details
Assay
Reference: J:105752 Wang Y, et al., The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci. 2006 Feb 22;26(8):2147-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5749546
Gene symbol: Fzd3
Gene name: frizzled class receptor 3
Antibody: Fz3 antibody
Results
Specimen 5E WT: embryonic day 18.0 (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: organ of Corti Present Regionally restricted 5E WT Expression is in hair cells and supporting cells.

Specimen 5E Fz6-/-: embryonic day 18.0; Fzd6tm1Nat/Fzd6tm1Nat (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: organ of Corti Strong Regionally restricted 5E Fz6-/- Expression is in hair cells and supporting cells.

Specimen 5E Fz3-/-: embryonic day 18.0; Fzd3tm1Nat/Fzd3tm1Nat (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: organ of Corti Absent 5E Fz3-/-

Specimen 5E Lp/Lp: embryonic day 18.0; Vangl2Lp/Vangl2Lp (more )
Note: Double labeled with phalloidin (red).
Structure Level Pattern Image Note
TS26: organ of Corti Absent 5E Lp/Lp

Specimen 6A utricle Lp/Lp: embryonic day 18.0; Vangl2Lp/Vangl2Lp (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: utricle Absent 6A utricle Lp/Lp

Specimen 6A utricle WT: embryonic day 18.5 (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: utricle Present Regionally restricted 6A utricle WT , 6A utricle merge Expression is at the plasma membrane in hair cells and supporting cells.

Specimen 6A crista Lp/Lp: embryonic day 18.5; Vangl2Lp/Vangl2Lp (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: crista ampullaris Absent 6A crista Lp/Lp

Specimen 6A crista WT: embryonic day 18.5 (more )
Note: Double labeled with phalloidin (red). Flat mount.
Structure Level Pattern Image Note
TS26: crista ampullaris Present Regionally restricted 6A crista merge , 6A crista WT Expression is at the plasma membrane in hair cells and supporting cells.

Specimen 7E: postnatal day 0 (more )
Note: Double labeled with phalloidin (red).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 7E Expression is in the apical region of the hair cells and pillar cells.

Specimen 7F: postnatal day 0 (more )
Note: Double labeled with phalloidin (red).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 7F Expression is in the apical region of the hair cells and pillar cells.

Specimen 7G: postnatal day 0 (more )
Note: Double labeled with phalloidin (red).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 7G Expression is in the apical region of the hair cells and pillar cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory