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Gene Expression Data
Assay Details
Assay
Reference: J:82310 Marin O, et al., Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Development. 2003 May;130(9):1889-901
Assay type: RNA in situ
MGI Accession ID: MGI:5702645
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Probe: Gad67 probe5
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen not shown +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted Expression was detected in tangentially migrating interneurons in the cortex.
Specimen not shown Slit1-/-; Slit2-/-: embryonic day 12.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted Expression was detected in tangentially migrating interneurons in the cortex. No obvious differences in number or laminar distribution of expressing cells within the cortex was seen in the mutant compared to wild type.
Specimen 5A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 5A Expression was detected in tangentially migrating interneurons in the cortex.
Specimen 5B: embryonic day 14.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 5B Expression was detected in tangentially migrating interneurons in the cortex. No obvious differences in number or laminar distribution of expressing cells within the cortex was seen in the mutant compared to wild type.
Specimen not shown +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present
Specimen not shown Slit1-/-;Ntn1-/-: embryonic day 18.5; Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present
Specimen 8H: embryonic day 18.5; Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 8H Expression was detected in interneurons.
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 8J There was no significant difference in expression in the triple mutant compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory