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Gene Expression Data
Assay Details
Assay
Reference: J:226614 Costello I, et al., Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev. 2015 Oct 15;29(20):2108-22
Assay type: RNA in situ
MGI Accession ID: MGI:5701403
Gene symbol: Afp
Gene name: alpha fetoprotein
Probe: AFP probe4
Probe preparation: Antisense RNA
Results
Specimen S3A Control--left: embryonic day 7.0 (more )
Note: late streak stage
Structure Level Pattern Image Note
TS10: primitive endoderm Present S3A Control left Expression is present in the visceral endoderm.
TS10: definitive endoderm Absent S3A Control left
Specimen S3A Control--center: embryonic day 7.25 (more )
Structure Level Pattern Image Note
TS10: primitive endoderm Present S3A Control center Expression is present in the visceral endoderm.
TS10: definitive endoderm Absent S3A Control center
Specimen S3A Control--right: embryonic day 7.5 (more )
Note: early headfold stage
Structure Level Pattern Image Note
TS11: primitive endoderm Present S3A Control right Expression is present in the visceral endoderm.
TS11: definitive endoderm Absent S3A Control right
Specimen S3A Mutant--left: embryonic day 7.0; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant. late streak stage
Structure Level Pattern Image Note
TS10: primitive endoderm Present S3A Lhx1 delta Epi left Expression is present in the visceral endoderm; these cells fail to be dispersed or displaced in the mutant.
TS10: definitive endoderm Absent S3A Lhx1 delta Epi left
Specimen S3A Mutant--center: embryonic day 7.25; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS10: primitive endoderm Present S3A Lhx1 delta Epi center Expression is present in the visceral endoderm; these cells fail to be dispersed or displaced in the mutant.
TS10: definitive endoderm Absent S3A Lhx1 delta Epi center
Specimen S3A Mutant--right: embryonic day 7.5; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant. early headfold stage
Structure Level Pattern Image Note
TS11: primitive endoderm Present S3A Lhx1 delta Epi right Expression is present in the visceral endoderm; these cells fail to be dispersed or displaced in the mutant.
TS11: definitive endoderm Absent S3A Lhx1 delta Epi right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory