Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:108240
Kusakabe T, et al., Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid. Dev Dyn. 2006 May;235(5):1300-9
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5700193
|
|
Gene symbol:
|
Nkx2-1
|
|
Gene name:
|
NK2 homeobox 1
|
|
|
Results
|
Specimen
1A:
embryonic day 12.5
(more  )
Specimen
1A:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
1B:
embryonic day 12.5; Nkx2-1tm1Shk/Nkx2-1 +
(more )
Specimen
1B:
(close )
|
Genetic Background:
|
involves: 129S4/SvJae
|
|
Mutant Allele(s):
|
Nkx2-1tm1Shk/Nkx2-1+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
1C:
(close )
|
Genetic Background:
|
involves: 129S4/SvJae
|
|
Mutant Allele(s):
|
Nkx2-1tm1Shk/Nkx2-1tm1Shk
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
2D/F:
embryonic day 13.5
(more )
Note: Double labeled: brown - Nkx2-1; red - Trp63 (assay MGI:5700196).
Specimen
2D/F:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Double labeled: brown - Nkx2-1; red - Trp63 (assay MGI:5700196).
|
Specimen
4B:
embryonic day 14.5
(more )
Specimen
4B:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: thyroid gland |
Strong |
Regionally restricted |
4B
|
High expression in primitive follicles, and faint expression in the partly fused ultimobranchial body.
|
Specimen
7C:
embryonic day 19.0; Nkx2-1tm1Shk/Nkx2-1 +
(more )
Specimen
7C:
(close )
|
Genetic Background:
|
involves: 129S4/SvJae
|
|
Mutant Allele(s):
|
Nkx2-1tm1Shk/Nkx2-1+
|
|
Age:
|
embryonic day 19.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: thyroid gland |
Present |
Regionally restricted |
7C
|
Expressed in small thyroid follicles.
|
|
Analysis Tools