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Gene Expression Data
Assay Details
Assay
Reference: J:217589 Kawakami E, et al., The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators. Mech Dev. 2015 Feb;135:31-42
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5698115
Gene symbol: Kdm2a
Gene name: lysine (K)-specific demethylase 2A
Reporter: lacZ
Direct Detection
Assay notes: Fixation with 1% paraformaldehyde, 0.2% glutaraldehyde.
Results
Specimen 2B Fbxl11+/-lacZ E8.5: embryonic day 8.5; Kdm2atm1b(KOMP)Mtok/Kdm2a+ (more )
Structure Level Pattern Image Note
TS13: embryo Weak 2B +/lacZ E8.5 Authors report low level of expression.

Specimen 2B Fbxl11+/-lacZ E10.5: embryonic day 10.5; Kdm2atm1b(KOMP)Mtok/Kdm2a+ (more )
Structure Level Pattern Image Note
TS17: embryo Present Widespread 2B +/lacZ E10.5 Expression throughout whole body.

Specimen 2B Fbxl11+/-lacZ E12.5: embryonic day 12.5; Kdm2atm1b(KOMP)Mtok/Kdm2a+ (more )
Structure Level Pattern Image Note
TS20: embryo Present Widespread 2B +/lacZ E12.5 Expression throughout whole body.
TS20: forebrain Strong 2B +/lacZ E12.5 Expression most prominent in forebrain and limbs.
TS20: limb Strong 2B +/lacZ E12.5 Expression most prominent in forebrain and limbs.

Specimen 2B Fbxl11+/-lacZ E14.5: embryonic day 14.5; Kdm2atm1b(KOMP)Mtok/Kdm2a+ (more )
Structure Level Pattern Image Note
TS22: embryo Present Widespread 2B +/lacZ E14.5
TS22: forebrain Strong 2B +/lacZ E14.5 Expression most prominent in forebrain and limbs.
TS22: limb Strong 2B +/lacZ E14.5 Expression most prominent in forebrain and limbs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory