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Gene Expression Data
Assay Details
Assay
Reference: J:213921 Yang L, et al., Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12097-102
Assay type: Recombinase reporter
MGI Accession ID: MGI:5697503
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Reporter: lacZ
Direct Detection
Results
Specimen 1C E15.0: embryonic day 15.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: tibia Present 1C E15.0 Recombinase reporter staining is detected in hypertrophic chondrocytes.
Specimen 1C E15.5: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: tibia Present 1C E15.5 Recombinase reporter staining is detected in hypertrophic chondrocyte-derived cells in the newly formed primary ossification center.
Specimen 1G C10cre::RLacZ X-gal top: postnatal day 10; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: tibia Present 1G C10cre::RLacZ X-gal top Recombinase reporter staining is detected in osteocytes and bone surface osteoblasts.
Specimen 1G C10cre::RLacZ X-gal/Col1a1 top: postnatal day 10; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant. Double labeled: blue - recombinase reporter; brown - Col1a1.
Structure Level Pattern Image Note
TS28: tibia Present 1G C10cre::RLacZ X-gal/Col1a1 top Some recombinase reporter staining is detected in Col1a1+ cells in the endosteum.
Specimen 1G C10cre::RLacZ X-gal bottom: postnatal day 10; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: tibia Present 1G C10cre::RLacZ X-gal bottom
Specimen 1G C10cre::RLacZ X-gal/Col1a1 bottom: postnatal day 10; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant. Double labeled: blue - recombinase reporter; brown - Col1a1.
Structure Level Pattern Image Note
TS28: tibia Present 1G C10cre::RLacZ X-gal/Col1a1 bottom Some recombinase reporter staining is detected in Col1a1+ cells in the endosteum.
Specimen 1H C10cre::LacZ left: postnatal month 3; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: tibia Present 1H C10cre::RLacZ left Recombinase reporter staining is detected at the chondro-osseous junction.
Specimen 1H C10cre::LacZ right: postnatal month 3; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Col10a1tm2.1(cre)Ksec/Col10a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: tibia Present 1H C10cre::RLacZ right Recombinase reporter staining is detected in cortical bone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory