Gene Expression Data
Assay Details
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Assay
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Reference:
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J:209154
Kelberman D, et al., Mutation of SALL2 causes recessive ocular coloboma in humans and mice. Hum Mol Genet. 2014 May 15;23(10):2511-26
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5694716
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Gene symbol:
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Pax2
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Gene name:
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paired box 2
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Antibody:
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anti-PAX2
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Detection system:
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Secondary antibody coupled to Alexa Fluor 594
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Results
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Specimen
5D:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Sall2tm1Jkoh/Sall2tm1Jkoh
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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sagittal section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: optic nerve |
Present |
Regionally restricted |
5D
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Expression is present in a wedge of cells surrounding the optic nerve head. No difference in expression is observed between mutant and control animals.
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Sall2tm1Jkoh/Sall2tm1Jkoh
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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sagittal section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: optic nerve |
Present |
Regionally restricted |
5E
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Expression is present in a wedge of cells surrounding the optic nerve head. No difference in expression is observed between mutant and control animals.
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Specimen
5H:
embryonic day 13.5; Sall2tm1Jkoh/Sall2 +
(more  )
Note: sagittal section
Specimen
5H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Sall2tm1Jkoh/Sall2+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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|
Note:
|
sagittal section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: optic nerve |
Present |
Regionally restricted |
5H
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Expression is present in a wedge of cells surrounding the optic nerve head.
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Specimen
5I:
embryonic day 13.5; Sall2tm1Jkoh/Sall2 +
(more )
Note: sagittal section
Specimen
5I:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Sall2tm1Jkoh/Sall2+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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|
Note:
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sagittal section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: optic nerve |
Present |
Regionally restricted |
5I
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Expression is present in a wedge of cells surrounding the optic nerve head.
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Analysis Tools
