Gene Expression Data
Assay Details
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Assay
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Reference:
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J:125029
Pelosi M, et al., ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Mol Cell Biol. 2007 Sep;27(17):6163-76
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5694457
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Gene symbol:
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Mapk1
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Gene name:
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mitogen-activated protein kinase 1
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Antibody:
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anti-phospho-p42/p44 MAPK
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Assay notes:
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This antibody recognizes the phosphorylated (activated) form of the protein.
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Results
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Specimen
E15.5 +/-:
embryonic day 15.5; Rock2tm1Sna/Rock2 +
(more  )
Note: section through forearm
Specimen
E15.5 +/-:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Rock2tm1Sna/Rock2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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section through forearm
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Specimen
E15.5 -/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Rock2tm1Sna/Rock2tm1Sna
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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section through forearm
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: forearm muscle |
Present |
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7_phospho p42/44 MAPK -/-
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The numbers of expressing cells are reduced in the mutant compared to controls, despite the apparently normal development of the extensor and flexor muscle groups.
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Analysis Tools
