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Gene Expression Data
Assay Details
Assay
Reference: J:199400 van den Heuvel DM, et al., Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5693248
Gene symbol: Rgma
Gene name: repulsive guidance molecule family member A
Antibody: Anti-Rgma (AF2458)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Weak Regionally restricted 1D Weak staining was noted on olfactory sensory neuron axons.
TS24: main olfactory bulb external plexiform layer Present Regionally restricted 1D Expression was detected in mitral cell axons in the internal and external plexiform layers.
TS24: main olfactory bulb internal plexiform layer Present Regionally restricted 1D Expression was detected in mitral cell axons in the internal and external plexiform layers.
TS24: main olfactory bulb prospective glomerular layer Weak 1D

Specimen 1H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory tract Present Regionally restricted 1H Expression was detected in axons of the lateral olfactory tract.
TS24: diencephalon Strong Regionally restricted 1H Expression was detected in axons of the anterior commissure.

Specimen 3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Strong Regionally restricted 3D' , 3D Expression was on axons.
TS24: cerebral cortex ventricular layer Present Regionally restricted 3D' , 3D Expression was detected in cells that had the appearance of radial glia.
TS24: cortical plate Present Regionally restricted 3D' , 3D Expression was detected in cells that had the appearance of radial glia.
TS24: corpus callosum Weak 3D Expression was on axons.

Specimen 3G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: corpus striatum Weak 3G Expression was on axons traversing the striatum.
TS24: cerebral internal capsule Strong Regionally restricted 3G Expression was on axons in the central part.

Specimen 4D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cortical layer I Present 4D
TS28: cortical layer II Present 4D
TS28: cortical layer III Present 4D
TS28: cortical layer V Present 4D

Specimen not shown P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebral internal capsule Present
TS28: corpus callosum Present

Specimen 4G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: corticospinal tract Strong 4G

Specimen 6D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 6D Expression was detected in the CA region and the fimbria.
TS24: dentate gyrus primordium Present Regionally restricted 6D Expression was detected in the inner molecular layer.
TS24: hippocampus ventricular layer Present 6D

Specimen 6M: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: fimbria hippocampus Present 6M
TS28: hippocampal commissure Present 6M
TS28: hippocampus molecular layer Present 6M
TS28: hippocampus stratum lacunosum Present 6M
TS28: hippocampus stratum oriens Present 6M

Specimen not shown Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent
TS28: hippocampus stratum lacunosum Weak
TS28: fimbria hippocampus Present Expression was reduced as compared to P5.

Specimen 8G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: medial habenular nucleus Present 8G

Specimen 8J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: fasciculus retroflexus Strong 8J

Specimen 9D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: fasciculus retroflexus Strong 9D

Specimen 11D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: deep cerebellar nucleus Present 11D
TS24: cerebellum external granule cell layer Present Regionally restricted 11D Expression was detected in cellular processes traversing the EGL.

Specimen 11J: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present 11J
TS28: cerebellum internal granule cell layer Present 11J

Specimen 11P: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 11P
TS28: cerebellum granule cell layer Present 11P
TS28: cerebellum molecular layer Present 11P Staining may represent the dendritic processes of Purkinje cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory