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Gene Expression Data
Assay Details
Assay
Reference: J:113404 Hoffmann K, et al., Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit. Am J Hum Genet. 2006 Aug;79(2):303-12
Assay type: RNA in situ
MGI Accession ID: MGI:5693111
Gene symbol: Chrng
Gene name: cholinergic receptor, nicotinic, gamma polypeptide
Probe: AChR gamma subunit cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: diaphragm Strong 7A
TS22: extrinsic ocular muscle Strong 7A
TS22: facial muscle Strong 7A
TS22: intercostal muscle Strong 7A
TS22: limb muscle Strong 7A
TS22: neck muscle Strong 7A
TS22: axial musculature Strong 7A Expression in paravertebral trunk muscles.
Specimen 7B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: limb musculature Present 7B
Specimen 7C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: limb musculature Present 7C
Specimen 7D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: limb muscle Strong 7D Expression is focal.
Specimen not shown: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: limb muscle Present
Specimen 7E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: limb muscle Ambiguous 7E Expression levels have decreased from those seen earlier.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory