Gene Expression Data
Assay Details
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Assay
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Reference:
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J:205268
Ahmad N, et al., Pitx3 directly regulates Foxe3 during early lens development. Int J Dev Biol. 2013;57(9-10):741-51
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5689311
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Gene symbol:
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Sox2
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Gene name:
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SRY (sex determining region Y)-box 2
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Results
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Specimen
2Aa/b:
embryonic day 10.5
(more  )
Specimen
2Aa/b:
(close  )
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Genetic Background:
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C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: lens pit |
Present |
Regionally restricted |
2A a/b
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Expression was restricted to the posterior half of the lens.
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Specimen
2Ac/d:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: lens pit |
Present |
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2A c/d
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Expression was detected throughout the lens in the mutant.
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Specimen
2Ae/f:
embryonic day 11.5
(more )
Specimen
2Ae/f:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: lens vesicle |
Present |
Regionally restricted |
2A e/f
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Expression was more obvious in the cells lining the anterior half of the lens and seemed to diminish in cells in the posterior half.
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Specimen
2Ag/h:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: lens vesicle |
Present |
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2A g/h
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Ectopic expression in the mutant lens was observed at E11.5.
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Analysis Tools
