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Gene Expression Data
Assay Details
Assay
Reference: J:40034 Labosky PA, et al., The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development. 1997 APR;124(7):1263-1274
Assay type: RNA in situ
MGI Accession ID: MGI:5688892
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl1 probe24
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3H: embryonic day 11.5; Foxb1tm1Blh/Foxb1tm1Blh (more )
Note: Unaffected -/- embryo
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 3H Expression in this mutant is the same as in wild-type embryos.
TS19: neural tube basal columns Present Regionally restricted 3H Expression in this mutant is the same as in wild-type embryos.

Specimen 3I: embryonic day 11.5; Foxb1tm1Blh/Foxb1tm1Blh (more )
Note: Affected -/- embryo, neural tube did not close.
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 3I Expression in this mutant is the same as in wild-type embryos.
TS19: neural tube basal columns Present Regionally restricted 3I Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory