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Gene Expression Data
Assay Details
Assay
Reference: J:153562 Acampora D, et al., Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm. Mech Dev. 2009 Oct;126(10):882-97
Assay type: RNA in situ
MGI Accession ID: MGI:5688691
Gene symbol: Lefty1
Gene name: left right determination factor 1
Results
Specimen 7F: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Present 7F
Specimen 7G: embryonic day 6.5; Otx2tm11Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Absent 7G Expression was absent in 5 of 7 mutants.
Specimen not shown: embryonic day 6.5; Otx2tm11Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Weak Expression was detected at a low level in only 2 of 7 mutants.
Specimen 7H: embryonic day 6.5; Otx2tm10Asim/Otx2tm10Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Present 7H Expression was detected in all the mutant embryos, but 4 of 11 revealed spotted disorganization.
Specimen 7I: embryonic day 6.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Absent 7I Expression was absent in 6 out of 11 mutants.
Specimen 7J: embryonic day 6.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Weak 7J Expression was decreased in 5 out of 11 mutants.
Specimen not shown: embryonic day 6.5; Otx2tm9Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Present All of the Otx2<delta3SS/GFP> mutant embryos showed normal expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory