Gene Expression Data
Assay Details
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Assay
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Reference:
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J:153562
Acampora D, et al., Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm. Mech Dev. 2009 Oct;126(10):882-97
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5688672
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Gene symbol:
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Dkk1
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Gene name:
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dickkopf WNT signaling pathway inhibitor 1
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Results
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Specimen
7A:
embryonic day 6.5
(more  )
Specimen
7A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Otx2tm11Asim/Otx2tm11Asim
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Otx2tm10Asim/Otx2tm10Asim
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS8: primitive endoderm |
Weak |
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7C
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Expression was reduced only in those embryos showing partial anteriorization and thickening of the visceral endoderm (n=3 out of 13).
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Specimen
7D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Otx2tm10Asim/Otx2tm11Asim
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Otx2tm10Asim/Otx2tm11Asim
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Otx2tm9Asim/Otx2tm11Asim
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS8: primitive endoderm |
Present |
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All of the Otx2<delta3SS/GFP> mutant embryos showed normal expression.
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Analysis Tools