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Gene Expression Data
Assay Details
Assay
Reference: J:153562 Acampora D, et al., Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm. Mech Dev. 2009 Oct;126(10):882-97
Assay type: RNA in situ
MGI Accession ID: MGI:5662549
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen S3O: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain Present S3O
Specimen S3P: embryonic day 10.5; Otx2tm8Asim/Otx2tm8Asim (more )
Structure Level Pattern Image Note
TS17: brain Present S3P There was no difference in expression between wild type and mutant.
Specimen S4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present S4A
Specimen S4E: embryonic day 9.5; Otx2tm9Asim/Otx2tm9Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present S4E In mutants with less severe head defects, expression was retained, although abnormal.
Specimen S4I: embryonic day 9.5; Otx2tm9Asim/Otx2tm9Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present S4I In mutants with a headless phenotype, expression was expanded rostrally.
Specimen S4M: embryonic day 9.5; Otx2tm9Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present S4M In mutants with a headless phenotype, expression was expanded rostrally.
Specimen 5B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present 5B
Specimen 5G: embryonic day 9.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present 5G Stable expression, although heavily abnormal, was maintained in the mutant.
Specimen 5L: embryonic day 9.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present 5L Stable expression, although heavily abnormal, was maintained in the mutant.
Specimen 5Q: embryonic day 9.5; Otx2tm11Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Absent 5Q
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory