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Gene Expression Data
Assay Details
Assay
Reference: J:131364 Cretekos CJ, et al., Regulatory divergence modifies limb length between mammals. Genes Dev. 2008 Jan 15;22(2):141-51
Assay type: RNA in situ
MGI Accession ID: MGI:5661467
Gene symbol: Prrx1
Gene name: paired related homeobox 1
Probe: Prx1 probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Uniform
Specimen 1D Mouse E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 1D Mouse_E10.5 Expression persists in anterior and posterior domains.
Specimen 1D Mouse E11: embryonic day 11.0-11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 1D Mouse_E11 Expression persists in anterior and posterior domains.
TS19: handplate mesenchyme Absent 1D Mouse_E11
Specimen 1D Mouse E12.0: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 1D Mouse_E12.0 Expression persists in anterior and posterior domains.
TS19: handplate mesenchyme Weak 1D Mouse_E12.0 Significantly lower levels of expression compared with more proximal domains.
Specimen 1D Mouse E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 1D Mouse_E12.5 Expression persists in anterior and posterior domains.
TS20: hand mesenchyme Weak 1D Mouse_E12.5 Significantly lower levels of expression compared with more proximal domains.
Specimen 1D Mouse E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 1D Mouse_E13.5 Expression in perichondrium surrounding digital condensations differentiating into chondrogenic elements.
Specimen S2D upper +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present S2D upper +/+
Specimen S2D delta/delta: embryonic day 12.5; Prrx1tm2Bhr/Prrx1tm2Bhr (more )
Structure Level Pattern Image Note
TS20: embryo Present S2D delta/delta No significant difference between mutant mice and their heterozygous and wild-type siblings.
Specimen S2D upper delta/+: embryonic day 12.5; Prrx1tm2Bhr/Prrx1+ (more )
Structure Level Pattern Image Note
TS20: embryo Present S2D upper delta/+
Specimen S2D lower +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present S2D lower +/+
Specimen S2D lower delta/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present S2D lower delta/+
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory