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Gene Expression Data
Assay Details
Assay
Reference: J:149253 Kulkarni RM, et al., NFATc1 regulates lymphatic endothelial development. Mech Dev. 2009 May-Jun;126(5-6):350-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660554
Gene symbol: Flt4
Gene name: FMS-like tyrosine kinase 4
Antibody: anti-VEGFR-3
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 1D: embryonic day 12.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS20: cardinal vein Absent 1D Not expressed in endothelial cells.
TS20: lymphatic system Present Uniform 1D Uniform bilateral expression in jugular lymph sacs endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen 1G: embryonic day 14.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1G Expressed in the trunk lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen 1H: embryonic day 14.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1H Expressed in the lung lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen 1I: embryonic day 14.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1I Expressed in the dermal lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen 1J: postnatal day 21 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS28: lymphatic vessel endothelium Present Regionally restricted 1J Expressed in the pulmonary lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen 2A: embryonic day 11.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 2A Expressed in endothelial cells. Coexpressed with Prox1 and Nfatc1.
TS19: lymphatic system Present Regionally restricted 2A Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Prox1 and Nfatc1.
Specimen 2C: embryonic day 11.5; Nfatc1tm1Glm/Nfatc1tm1Glm (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS19: cardinal vein Present 2C Coexpressed with Prox1 in endothelial cells.
TS19: lymphatic system Present 2C Coexpressed with Prox1 in endothelial cells.
Specimen S1C: embryonic day 12.5 (more )
Note: Triple labeled: red - Flt4; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS20: lymphatic system Present Uniform S1C Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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