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Gene Expression Data
Assay Details
Assay
Reference: J:149253 Kulkarni RM, et al., NFATc1 regulates lymphatic endothelial development. Mech Dev. 2009 May-Jun;126(5-6):350-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660552
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C/D: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS20: cardinal vein Present Regionally restricted 1C , 1D Expressed in endothelial cells.
TS20: lymphatic system Present Uniform 1D , 1C Uniform bilateral expression in jugular lymph sacs endothelial cells. Coexpressed with Prox1 and Flt4.
Specimen 1E: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted 1E Expressed in jugular lymph sacs endothelial cells.
TS20: cardinal vein Present Regionally restricted 1E Expressed in endothelial cells.
Specimen 1F: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted 1F Expressed in jugular lymph sacs endothelial cells.
TS20: cardinal vein Present Regionally restricted 1F Expressed in endothelial cells.
Specimen 1G: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1G Expressed in the trunk lymphatics.
Specimen 1H: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1H Expressed in the lung lymphatics.
Specimen 1I: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 1I Expressed in the dermal lymphatics.
Specimen 1J: postnatal day 21 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS28: lymphatic vessel endothelium Present Regionally restricted 1J Expressed in the pulmonary lymphatics.
Specimen 2A: embryonic day 11.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 2A Expressed in endothelial cells. Coexpressed with Nfatc1 and Flt4.
TS19: lymphatic system Present Regionally restricted 2A Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Nfatc1 and Flt4.
Specimen 2B: embryonic day 11.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 2B Expressed in endothelial cells. Coexpressed with Nfatc1.
TS19: lymphatic system Present Regionally restricted 2B Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Nfatc1.
Specimen 2C: embryonic day 11.5; Nfatc1tm1Glm/Nfatc1tm1Glm (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS19: cardinal vein Present 2C Coexpressed with Flt4.
TS19: lymphatic system Present 2C Coexpressed with Flt4.
Specimen 2D: embryonic day 11.5; Nfatc1tm1Glm/Nfatc1tm1Glm (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS19: cardinal vein Present 2D
TS19: lymphatic system Present 2D
Specimen S1B/C: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Flt4 (assay MGI:5660554).
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted S1C , S1B Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen S1D: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted S1D Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen S1E: embryonic day 12.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted S1E Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen S1F: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1F Expressed in the dermal lymphatics.
Specimen S1G: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1G Expressed in the dermal lymphatics.
Specimen S1H: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1H Expressed in the pulmonary lymphatics.
Specimen S1I: embryonic day 14.5 (more )
Note: Triple labeled: blue - Prox1; green - Nfatc1 (assay MGI:5660396); red - GSL-B4 isolectin.
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1I Expressed in the pulmonary lymphatics.
Specimen S2A: embryonic day 11.5 (more )
Note: Double labeled: blue - Prox1; red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS19: lymphatic system Present Regionally restricted S2A Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Specimen S2B: embryonic day 11.5; Nfatc1tm1Glm/Nfatc1tm1Glm (more )
Note: Double labeled: blue - Prox1; red - Pdpn (assay MGI:5660608).
Structure Level Pattern Image Note
TS19: lymphatic system Present Regionally restricted S2B Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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