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Gene Expression Data
Assay Details
Assay
Reference: J:35538 Mallamaci A, et al., OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area. Mech Dev. 1996 Aug;58(1-2):165-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5649312
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: anti-OTX2
Detection system: Secondary antibody coupled to alkaline phosphatase
Assay notes: Tissue was frozen in cooled isopentane and then immersed in methanol.
Results
Specimen 2a: embryonic day 5.5 (more )
Note: longitudinal section
Structure Level Pattern Image Note
TS7: epiblast Present Widespread 2a
TS7: primitive endoderm Present Widespread 2a Expression is present in the hypoblast.
TS7: extraembryonic component Absent 2a
Specimen 2b: embryonic day 6.0 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS8: epiblast Present Widespread 2b
TS8: primitive endoderm Present Widespread 2b Expression is present in the hypoblast.
TS8: extraembryonic component Absent 2b
Specimen 7n: embryonic day 13.0 (more )
Note: Transverse section. Double labeled: gray/blue - Otx2; brown - Gnrh1 (assay MGI:5649374).
Structure Level Pattern Image Note
TS21: nose Present Single cells 7n Some expressing cells are double labeled with Gnrh1/LHRH.
Specimen 7o: embryonic day 13.0 (more )
Note: Transverse section. Double labeled: gray/blue - Otx2; brown - Gfap (assay MGI:5649375).
Structure Level Pattern Image Note
TS21: nose Present Regionally restricted 7o Expression is present in glial cells ensheathing the olfactory and vomero-nasal nerves.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory