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Gene Expression Data
Assay Details
Assay
Reference: J:119927 Yu HM, et al., Impaired neural development caused by inducible expression of Axin in transgenic mice. Mech Dev. 2007 Feb;124(2):146-56
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5648225
Gene symbol: Axin2
Gene name: axin 2
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.5; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS13: neural fold Strong Regionally restricted 2A Expression was detected in the lateral margin of the neural fold at the boundary between surface and neural ectoderms.

Specimen 2B: embryonic day 9.5; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS15: central nervous system Strong Regionally restricted 2B Expression was strong along the dorsal midline of the central nervous system.

Specimen 2C: embryonic day 10.5; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted 2C Expression was detected in the dorsal neural tube.
TS17: branchial arch Present 2C

Specimen 2D: embryonic day 12.5; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 2D Expression was detected in the dorsal midline of the central nervous system.
TS20: face Present Regionally restricted 2D Expression was detected in the area around the eyes and other facial structures that are derivatives of the cranial neural crest.
TS20: outer ear Present 2D
TS20: vibrissa follicle Present 2D

Specimen 2E: embryonic day 8.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present 2E
TS13: neural fold Present Regionally restricted 2E Expression was detected in the lateral margin of the neural fold at the boundary between surface and neural ectoderms.

Specimen 2F: embryonic day 9.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS15: branchial arch Present 2F
TS15: migrating neural crest Present 2F

Specimen 2G: embryonic day 10.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 2G Inset shows an enlargement of the branchial arch staining.

Specimen 3A: embryonic day 9.0; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS14: central nervous system Present Regionally restricted 3A Expression was detected in neuroepithelial cells in the dorsal neural tube.
TS14: branchial arch Present 3A
TS14: migrating neural crest Present 3A

Specimen 3C: embryonic day 10.5; Axin2tm1Wbm/Axin2+ (more )
Note: Fixative: 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted 3C Expression was detected in neuroepithelial cells in the dorsal neural tube.
TS17: branchial arch Present 3C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory