Gene Expression Data
Assay Details
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Assay
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Reference:
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J:50809
Bora N, et al., Transient overexpression of the Microphthalmia gene in the eyes of Microphthalmia vitiligo mutant mice. Dev Dyn. 1998 Nov;213(3):283-92
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5645668
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Gene symbol:
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Mitf
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Gene name:
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melanogenesis associated transcription factor
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Probe:
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Mitf cDNA6
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5B:
embryonic day 9.5
(more  )
Specimen
5B:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5C:
embryonic day 10.5
(more )
Specimen
5C:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: eye |
Present |
Graded |
5C
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Expression is stronger dorsally.
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Specimen
5D:
embryonic day 11.5
(more )
Specimen
5D:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: eye |
Present |
Graded |
5D
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Expression is stronger dorsally.
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Specimen
5E:
embryonic day 14.5
(more )
Specimen
5E:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: eye |
Present |
Regionally restricted |
5E
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Expression is at the anterior portion of the eye.
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Specimen
5F:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5G:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5H:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5I:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5J:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: eye |
Present |
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5J
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Expression was similar to wild-type embryos.
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Specimen
6A:
embryonic day 9.0
(more )
Specimen
6A:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6B:
embryonic day 9.0
(more )
Specimen
6B:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6C:
embryonic day 9.5
(more )
Specimen
6C:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: eye |
Present |
Regionally restricted |
6C
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Expression is diminished toward the anterior region.
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Specimen
6D:
embryonic day 10.0
(more )
Specimen
6D:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: optic cup |
Present |
Regionally restricted |
6D
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Expression is in the retinal pigmented epithelium, absent in the future retina.
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Specimen
6E:
embryonic day 10.5
(more )
Specimen
6E:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
|
4% Paraformaldehyde
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|
Embedding:
|
Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
6E
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Expression is in the retinal pigmented epithelium and is diminished at the retinal margin.
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Specimen
6F:
embryonic day 11.5
(more )
Specimen
6F:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6G:
embryonic day 14.5
(more )
Specimen
6G:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: pigmented retinal epithelium |
Present |
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6G
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Expression is strongest at the margin of the retinal pigmented epithelium and the retina.
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| TS22: eye |
Weak |
Regionally restricted |
6G
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Expression is at the peripheral region.
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Specimen
6H:
embryonic day 14.6
(more )
Specimen
6H:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6I:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6J:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
|
Mitfmi-vit/Mitfmi-vit
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|
Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6K:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
7A:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
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Age:
|
embryonic day 10.5
|
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk |
Present |
Regionally restricted |
7A
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Expression is in cell populations located bilaterally on either side of the neural tube.
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Specimen
7B:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Mitfmi-vit/Mitfmi-vit
|
|
Age:
|
embryonic day 10.5
|
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk |
Present |
Regionally restricted |
7B
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Expression is in cell populations located bilaterally on either side of the neural tube.
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Specimen
7C:
embryonic day 9.5
(more )
Specimen
7C:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown:
embryonic day 16.0
(more )
Specimen
not shown:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 16.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown E7.5:
embryonic day 7.5
(more )
Specimen
not shown E7.5:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
not shown E8.5:
embryonic day 8.5
(more )
Specimen
not shown E8.5:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 8.5
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Sex:
|
Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
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