Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:79898
Kochilas L, et al., The role of neural crest during cardiac development in a mouse model of DiGeorge syndrome. Dev Biol. 2002 Nov 1;251(1):157-66
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:5645318
|
|
Gene symbol:
|
Edn1
|
|
Gene name:
|
endothelin 1
|
|
Probe:
|
ET-1 probe2
|
|
Probe preparation:
|
Antisense labelled with radioactivity
|
|
Visualized with:
|
Autoradiography
|
|
|
Results
|
Specimen
not shown wt:
embryonic day 9.5
(more  )
Specimen
not shown wt:
(close  )
|
Genetic Background:
|
involves: 129 * C57BL/6J * SJL
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
not shown Tbx1-/-:
(close )
|
Genetic Background:
|
involves: 129/Sv * C57BL/6J * SJL
|
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: branchial arch artery |
Present |
|
|
There are gross aortic arch abnormalities in the mutants. However, expression is as in wild type; it is present in the aortic arch artery endothelium.
|
Specimen
3E:
embryonic day 11.5
(more )
Note: cross section
Specimen
3E:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6J * SJL
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
cross section
|
Specimen
3F:
(close )
|
Genetic Background:
|
involves: 129/Sv * C57BL/6J * SJL
|
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
cross section
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: branchial arch artery |
Present |
|
3F
|
There are gross aortic arch abnormalities in the mutants. However, expression is as in wild type; it is present in the aortic arch artery endothelium.
|
|
Analysis Tools