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Gene Expression Data
Assay Details
Assay
Reference: J:221424 Miwa H, et al., Generation and characterization of PDGFRalpha-GFPCreER(t2) knock-In mouse line. Genesis. 2015 May;53(5):329-36
Assay type: Recombinase reporter
MGI Accession ID: MGI:5644486
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Reporter: lacZ
Direct Detection
Assay notes: Induction was achieved by intraperitoneal injection of 1 mg/ml tamoxifen dissolved in corn oil at specified time. Recombinase reporter staining is not detected in mice treated with vehicle alone.
Results
Specimen 3d hindbrain: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS15: future hindbrain Present 3d hindbrain However, cre/EGFP fusion expression is not detected in neuroepithelial cells.
Specimen 3d forebrain: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS15: future forebrain Present 3d forebrain However, cre/EGFP fusion expression is not detected in neuroepithelial cells.
Specimen 3d neural tube: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS15: neural tube Present 3d neural tube left , 3d neural tube right However, cre/EGFP fusion expression is not detected in neuroepithelial cells.
Specimen 3c: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS15: embryo Present 3c
Specimen 4a left: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS22: embryo Present 4a left
TS22: face mesenchyme Absent 4a left
Specimen 4a right: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E9.5.
Structure Level Pattern Image Note
TS22: embryo Present 4a right
TS22: face mesenchyme Present 4a right
Specimen 4b eye left: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS22: face mesenchyme Absent 4b eye left
Specimen 4b eye right: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E9.5.
Structure Level Pattern Image Note
TS22: face mesenchyme Present 4b eye right
Specimen 4b spinal cord left: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS22: embryo mesenchyme Present 4b spinal cord left
Specimen 4b spinal cord right: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E9.5.
Structure Level Pattern Image Note
TS22: embryo mesenchyme Present 4b spinal cord right
Specimen 4b lung/heart/forelimb left/4c top left: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS22: forelimb Present 4c top left , 4b lung/heart/forelimb left
TS22: heart Present 4c top left , 4b lung/heart/forelimb left
TS22: limb mesenchyme Present 4c top left , 4b lung/heart/forelimb left
TS22: limb skin Present 4c top left , 4b lung/heart/forelimb left
TS22: lung mesenchyme Present 4c top left , 4b lung/heart/forelimb left
TS22: lung Present 4b lung/heart/forelimb left , 4c top left Recombinase reporter staining is detected in the lung dermis.
Specimen 4b lung/heart/forelimb right/4c top right: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E9.5.
Structure Level Pattern Image Note
TS22: forelimb Present 4b lung/heart/forelimb right , 4c top right
TS22: limb mesenchyme Present 4b lung/heart/forelimb right , 4c top right
TS22: limb skin Present 4b lung/heart/forelimb right , 4c top right
TS22: lung mesenchyme Present 4b lung/heart/forelimb right , 4c top right
TS22: heart Absent 4c top right , 4b lung/heart/forelimb right
TS22: lung Present 4c top right , 4b lung/heart/forelimb right Recombinase reporter staining is detected in the lung dermis.
Specimen 4b kidney left/4c bottom left: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E7.5.
Structure Level Pattern Image Note
TS22: metanephros Absent 4c bottom left , 4b kidney left
Specimen 4b kidney right/4c bottom right: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ (more )
Note: Conditional mutant. Treated with tamoxifen at E9.5.
Structure Level Pattern Image Note
TS22: metanephros Present 4b kidney right , 4c bottom right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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