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Gene Expression Data
Assay Details
Assay
Reference: J:169107 Kunwar AJ, et al., Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5642096
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved-Caspase3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4G: embryonic day 12.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 4G
Specimen 4H: embryonic day 12.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong 4H There is an increase in apoptotic neurons in this mutant.
Specimen S4C: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4C
Specimen S4D: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4D Expression in this mutant is similar to wild-type.
Specimen S4E: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4E
Specimen S4F: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4F Expression in this mutant is similar to wild-type.
Specimen S4Q Table E12.5 DHET: embryonic day 12.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E12.5 DKO: embryonic day 12.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E14.5 DHET: embryonic day 14.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E14.5 KO: embryonic day 14.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Strong Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory