About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:169107 Kunwar AJ, et al., Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5642096
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved-Caspase3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4G: embryonic day 12.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 4G
Specimen 4H: embryonic day 12.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong 4H There is an increase in apoptotic neurons in this mutant.
Specimen S4C: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4C
Specimen S4D: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4D Expression in this mutant is similar to wild-type.
Specimen S4E: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4E
Specimen S4F: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present S4F Expression in this mutant is similar to wild-type.
Specimen S4Q Table E12.5 DHET: embryonic day 12.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E12.5 DKO: embryonic day 12.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E14.5 DHET: embryonic day 14.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Specimen S4Q Table E14.5 KO: embryonic day 14.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Strong Quantitative analysis was carried out by measuring the mean apoptotic area of active caspase-3-positive neurons per ganglionic area.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory