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Gene Expression Data
Assay Details
Assay
Reference: J:208871 Gong L, et al., Sumoylation differentially regulates Sp1 to control cell differentiation. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5574-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5638787
Gene symbol: Sp1
Gene name: trans-acting transcription factor 1
Antibody: Anti-Sp1
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 4A upper: embryonic day 11.5 (more )
Note: Double labeled: red - Sp1; green - Sumo1 (assay MGI:5638765).
Structure Level Pattern Image Note
TS19: lens vesicle anterior epithelium Present Uniform 4A Sumo1/Sp1 , 4A Merge upper , 4A Sp1 upper Expression co-localized with Sumo1.
TS19: lens vesicle Present Regionally restricted 4A Sumo1/Sp1 , 4A Sp1 upper , 4A Merge upper Expression co-localized with Sumo1 in the posterior differentiating cells of the lens vesicle.
Specimen 4A lower: embryonic day 11.5 (more )
Note: Double labeled: red - Sp1; green - Sumo2 (assay MGI:5638767) and Sumo3 (assay MGI:5639084).
Structure Level Pattern Image Note
TS19: lens vesicle anterior epithelium Present 4A Merge lower , 4A Sp1 lower , 4A Sumo2/3/Sp1 Expression co-localized with Sumo2/3.
TS19: lens vesicle Present Regionally restricted 4A Sp1 lower , 4A Merge lower , 4A Sumo2/3/Sp1 Co-localization with Sumo2/3 was greatly reduced in the posterior cells undergoing differentiation into primary lens fibers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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