Gene Expression Data
Assay Details
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Assay
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Reference:
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J:46409
Hirsch MR, et al., Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5637691
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Gene symbol:
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Phox2b
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Gene name:
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paired-like homeobox 2b
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Probe:
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Phox2b probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6C:
embryonic day 10.5
(more  )
Specimen
6C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
6C
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Expression was detected in the locus coeruleus precursors.
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| TS17: rhombomere 4 |
Strong |
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6C
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| TS17: midbrain |
Present |
Regionally restricted |
6C
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Expression was detected in the primordia of the nuclei of the IIIrd (oculomotor) and IVth (trochlear) cranial nerves.
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
6D
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Expression was strong in the fourth rhombomere, as in wild type. There was no expression in the expected location of the locus coeruleus neurons, which appear to never develop in the mutant.
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| TS17: rhombomere 4 |
Strong |
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6D
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| TS17: midbrain |
Present |
Regionally restricted |
6D
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Expression was detected in the primordia of the nuclei of the IIIrd (oculomotor) and IVth (trochlear) cranial nerves, as in wild type.
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Analysis Tools