Gene Expression Data
Assay Details
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Assay
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Reference:
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J:46409
Hirsch MR, et al., Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5637588
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Gene symbol:
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Th
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Gene name:
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tyrosine hydroxylase
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Results
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Specimen
5I:
embryonic day 13.5; Ascl1tm1And/Ascl1 +
(more  )
Specimen
5I:
(close  )
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Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: pons |
Present |
Regionally restricted |
5I
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Expression was detected in the locus coeruleus anlage.
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Specimen
5J:
(close )
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Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: pons |
Ambiguous |
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5J
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There was no expression in the expected location of the locus coeruleus neurons, which appear to never develop in the mutant.
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Specimen
7G:
embryonic day 13.5; Ascl1tm1And/Ascl1 +
(more )
Specimen
7G:
(close )
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Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
7G
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Expression was detected in the substantia nigra and ventral tegmental area of the midbrain.
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Specimen
7H:
(close )
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Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
7H
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Expression was detected in the substantia nigra and ventral tegmental area of the midbrain, as in wild type.
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