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Gene Expression Data
Assay Details
Assay
Reference: J:78589 Tarabykin V, et al., Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. Development. 2001 Jun;128(11):1983-93
Assay type: RNA in situ
MGI Accession ID: MGI:5635121
Gene symbol: Svet1
Gene name: subventricular expressed transcript 1
Probe: Svet1 probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: neocortex Present Regionally restricted 1A Expression detected in the most anterolateral part of neotex, but absent in more medial parts.

Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present 1B Authors state that expression begins immediately after the first appearance of the SVZ.
TS21: cerebral cortex Present Regionally restricted 1B Expression in rostrolateral cortex, but no expression in more posterior parts of cortex.

Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present Uniform 1E In developmentally more advanced littermates at E13.5, expression is evenly distributed throughout whole neocortical SVZ.

Specimen 1H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present 1H
TS21: cerebral cortex ventricular layer Absent 1H

Specimen 1K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present 1K

Specimen 1N: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 1N No expression in the neocortex outside of the SVZ.
TS23: piriform cortex Present Regionally restricted 1N Expression in the piriform plate of the piriform cortex.

Specimen 1Q: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 1Q Expression confined to the SVZ.

Specimen 2B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present 2B
TS26: cerebral cortex intermediate zone Present 2B Expression particularly strong in the intermediate zone, which consists of migrating neurons, most fated for upper layers.
TS26: cortical plate Present Regionally restricted 2B Some expression in cells within outermost part of the cortical plate.
TS26: neocortex Present 2B Expression in most lateral parts of neocortex respecting lateral-to-medial gradient of neurogenesis, as well as anterior-posterior gradient of corticogenesis.

Specimen 2E: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cortical layer II Present 2E Expression in upper layers (II-IV).
TS27: cortical layer III Present 2E Expression in upper layers (II-IV).
TS27: cortical layer IV Present 2E Expression in upper layers (II-IV).

Specimen not shown P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: neocortex Present Regionally restricted Abundant expression in somatosensory cortex.
TS27: cingulate cortex Absent Authors state that expression is almost absent in the cingulate area.

Specimen not shown P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted Expression in subpopulations of cells in layers IV, III and II.
TS28: cortical layer III Present Regionally restricted Expression in subpopulations of cells in layers IV, III and II.
TS28: cortical layer IV Present Regionally restricted Expression in subpopulations of cells in layers IV, III and II.

Specimen not shown P60: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent No expression in cortex beyond P60.

Specimen 3A,B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: midbrain Present Scattered 3A/B Expression in some postmitotic cells of the tegmentum and tectum.
TS21: midbrain ventricular layer Present 3A/B Expression in the ventricular zone and adjacent region of the inferior colliculus.

Specimen 3C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basal columns Present Regionally restricted 3C/D Expression in some neurons within the ventral horn of the spinal cord.

Specimen 3E,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 3E/F Expression in some postmitotic cells of the tegmentum and tectum.
TS22: midbrain ventricular layer Present 3E/F Expression in the ventricular zone and adjacent region of the inferior colliculus.

Specimen 3G,H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: telencephalon septum Present Regionally restricted 3G/H Expression in some differentiating fields of the septum.

Specimen 5A,C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present 5A , 5C
TS27: cerebral cortex intermediate zone Present 5A , 5C
TS27: cortical plate Present Regionally restricted 5C , 5A Expression in lower part of cortical plate.

Specimen 5B,D: postnatal day 0; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present Regionally restricted 5D , 5B Authors report the same level expression within the SVZ in mutant and wild-type newborns.
TS27: cerebral cortex Present Regionally restricted 5B , 5D No expression in outermost part of cortex.

Specimen 5E,G: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Regionally restricted 5E , 5G Expression within upper third of cortical plate, where layer II-IV neurons are located.
TS27: cerebral cortex Present Regionally restricted 5E , 5G Expression most abundant in somatosensory cortex.

Specimen 5F,H: postnatal day 3; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Regionally restricted 5F , 5H Expression in lower part of cortical plate.
TS27: cerebral cortex Present Regionally restricted 5H , 5F Expression most abundant in somatosensory cortex.

Specimen 6B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 6B

Specimen 6E: embryonic day 15.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present Regionally restricted 6E Authors state that expression was greatly affected in neocortical SVZ, but preserved in the SVZ of the cingulate cortex. Expression absent in lateral cortex, but present in reduced amounts in SVZ of most medial neocortex.

Specimen 6H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 6H Most expressing cells are migrating in the wild-type cortex at this stage.

Specimen 6K: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex intermediate zone Absent 6K Expressing cells are missing in the mutant intermediate zone.
TS26: cerebral cortex subventricular zone Absent 6K

Specimen 7B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: frontal cortex Present 7B

Specimen 7E: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: frontal cortex Present 7E

Specimen 7H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: occipital cortex Present Regionally restricted 7H Expression in SVZ cell of occipital cortex.

Specimen 7K: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: occipital cortex Present Regionally restricted 7K Expression in fewer SVZ cells of occipital cortex.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory