Results
|
Specimen
1A:
embryonic day 13.5
(more )
Specimen
1A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: neocortex |
Present |
Regionally restricted |
1A
|
Expression detected in the most anterolateral part of neotex, but absent in more medial parts.
|
Specimen
1B:
embryonic day 13.5
(more )
Specimen
1B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
1E:
embryonic day 13.5
(more )
Specimen
1E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: cerebral cortex subventricular zone |
Present |
Uniform |
1E
|
In developmentally more advanced littermates at E13.5, expression is evenly distributed throughout whole neocortical SVZ.
|
Specimen
1H:
embryonic day 13.5
(more )
Specimen
1H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
1K:
embryonic day 13.5
(more )
Specimen
1K:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
1N:
embryonic day 15.5
(more )
Specimen
1N:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
1Q:
embryonic day 15.5
(more )
Specimen
1Q:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
2B:
embryonic day 18.5
(more )
Specimen
2B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
2E:
postnatal day 2
(more )
Specimen
2E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
not shown P2:
postnatal day 2
(more )
Specimen
not shown P2:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: neocortex |
Present |
Regionally restricted |
|
Abundant expression in somatosensory cortex.
|
TS27: cingulate cortex |
Absent |
|
|
Authors state that expression is almost absent in the cingulate area.
|
Specimen
not shown P14:
postnatal day 14
(more )
Specimen
not shown P14:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cortical layer II |
Present |
Regionally restricted |
|
Expression in subpopulations of cells in layers IV, III and II.
|
TS28: cortical layer III |
Present |
Regionally restricted |
|
Expression in subpopulations of cells in layers IV, III and II.
|
TS28: cortical layer IV |
Present |
Regionally restricted |
|
Expression in subpopulations of cells in layers IV, III and II.
|
Specimen
not shown P60:
postnatal day 60
(more )
Specimen
not shown P60:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 60
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
3A,B:
embryonic day 13.5
(more )
Specimen
3A,B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
3C,D:
embryonic day 14.5
(more )
Specimen
3C,D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: basal columns |
Present |
Regionally restricted |
3C/D
|
Expression in some neurons within the ventral horn of the spinal cord.
|
Specimen
3E,F:
embryonic day 14.5
(more )
Specimen
3E,F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
3E/F
|
Expression in some postmitotic cells of the tegmentum and tectum.
|
TS22: midbrain ventricular layer |
Present |
|
3E/F
|
Expression in the ventricular zone and adjacent region of the inferior colliculus.
|
Specimen
3G,H:
embryonic day 18.5
(more )
Specimen
3G,H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: telencephalon septum |
Present |
Regionally restricted |
3G/H
|
Expression in some differentiating fields of the septum.
|
Specimen
5A,C:
postnatal day 0
(more )
Specimen
5A,C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5B,D:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Relnrl/Relnrl
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5E,G:
postnatal day 3
(more )
Specimen
5E,G:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal day 3
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: cortical plate |
Present |
Regionally restricted |
5E
,
5G
|
Expression within upper third of cortical plate, where layer II-IV neurons are located.
|
TS27: cerebral cortex |
Present |
Regionally restricted |
5E
,
5G
|
Expression most abundant in somatosensory cortex.
|
Specimen
5F,H:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Relnrl/Relnrl
|
Age:
|
postnatal day 3
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: cortical plate |
Present |
Regionally restricted |
5F
,
5H
|
Expression in lower part of cortical plate.
|
TS27: cerebral cortex |
Present |
Regionally restricted |
5H
,
5F
|
Expression most abundant in somatosensory cortex.
|
Specimen
6B:
embryonic day 15.5
(more )
Specimen
6B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
6E:
(close )
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
Mutant Allele(s):
|
Pax6Sey/Pax6Sey
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: cerebral cortex subventricular zone |
Present |
Regionally restricted |
6E
|
Authors state that expression was greatly affected in neocortical SVZ, but preserved in the SVZ of the cingulate cortex. Expression absent in lateral cortex, but present in reduced amounts in SVZ of most medial neocortex.
|
Specimen
6H:
embryonic day 18.5
(more )
Specimen
6H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex |
Present |
Regionally restricted |
6H
|
Most expressing cells are migrating in the wild-type cortex at this stage.
|
Specimen
6K:
(close )
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
Mutant Allele(s):
|
Pax6Sey/Pax6Sey
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
7B:
embryonic day 18.5
(more )
Specimen
7B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
7E:
(close )
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
Mutant Allele(s):
|
Pax6Sey/Pax6Sey
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
7H:
embryonic day 18.5
(more )
Specimen
7H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: occipital cortex |
Present |
Regionally restricted |
7H
|
Expression in SVZ cell of occipital cortex.
|
Specimen
7K:
(close )
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
Mutant Allele(s):
|
Pax6Sey/Pax6Sey
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: occipital cortex |
Present |
Regionally restricted |
7K
|
Expression in fewer SVZ cells of occipital cortex.
|
|