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Gene Expression Data
Assay Details
Assay
Reference: J:213957 Howard JM, et al., Tcf3 expression marks both stem and progenitor cells in multiple epithelia. Development. 2014 Aug;141(16):3143-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5629679
Gene symbol: Tcf7l1
Gene name: transcription factor 7 like 1 (T cell specific, HMG box)
Antibody: anti-Tcf3
Detection system: Secondary antibody
Results
Specimen 1D: postnatal day 30 (more )
Note: Back skin. Double labeled: green - Tcf7l1; red - Mki67 (assay MGI:5629680).
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 1D Expression is present in non-proliferating cells.

Specimen 1E: postnatal day 30 (more )
Note: Back skin. Double labeled: green - Tcf7l1; red - Lef1 (assay MGI:5629681).
Structure Level Pattern Image Note
TS28: coat hair follicle Present 1E
TS28: hair outer root sheath Present 1E

Specimen 1G: postnatal day 0 (more )
Note: Back skin.
Structure Level Pattern Image Note
TS27: coat hair follicle Present 1G

Specimen 1H: postnatal day 0 (more )
Note: Back skin. Double labeled: red - Tcf7l1 protein; green - Tcf7l1 reporter (assay MGI:5629701).
Structure Level Pattern Image Note
TS27: coat hair follicle Present 1H

Specimen 1I: postnatal day 0 (more )
Note: Back skin. Double labeled: red - Tcf7l1 protein; green - Tcf7l1 reporter (assay MGI:5629701).
Structure Level Pattern Image Note
TS27: coat hair follicle Present 1I

Specimen S2B: postnatal day 21 (more )
Note: Double labeled: green - Tcf7l1; red - Pecam1 (assay MGI:5629711).
Structure Level Pattern Image Note
TS28: blood vessel Present S2B Expression present in dermal blood vessels.

Specimen 4A: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: foot skin Present Regionally restricted 4A Expression is present ubiquitously throughout the basal layer of the stratified paw skin.

Specimen 4B: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: foot skin Present Regionally restricted 4B Expression is present ubiquitously throughout the basal layer of the stratified paw skin, as well as in occasional suprabasal cells.

Specimen 4C: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: plantar pad Present Regionally restricted 4C Expression is present in the thick skin overlying the digital pads.

Specimen 5A: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present 5A Expression is present throughout.

Specimen 5B: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present 5B Expression is present throughout the basal layer, as well as in some suprabasal cells.

Specimen S3A: postnatal adult (more )
Note: Double labeled: green - Tcf7l1; red - Loricrin (assay MGI:5629718).
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present S3A Expression is present in the differentiating granular layer.

Specimen 6A: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: tongue epithelium Present Regionally restricted 6A Expression is present at varying levels throughout the basal layer of the lingual mucosa; the highest levels of expression are at the base of the interpapillary pits.

Specimen 6B: postnatal (more )
Note: Double labeled: green - Tcf7l1; red - Krt5 (assay MGI:5629739).
Structure Level Pattern Image Note
TS28: tongue epithelium Present Regionally restricted 6B Expression is present at varying levels throughout the basal layer of the lingual mucosa; the highest levels of expression are at the base of the interpapillary pits.

Specimen S3B: postnatal adult (more )
Note: Double labeled: green - Tcf7l1; red - Loricrin (assay MGI:5629718).
Structure Level Pattern Image Note
TS28: tongue epithelium Present Regionally restricted S3B Expression is present in the differentiating granular layer. There is moderate expression in some suprabasal cells.

Specimen S5C: postnatal day 21 (more )
Note: Double labeled: green - Tcf7l1; red - Mki67 (assay MGI:5629680).
Structure Level Pattern Image Note
TS28: tongue epithelium Present S5C , S5C''


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory