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Gene Expression Data
Assay Details
Assay
Reference: J:98302 Altick AL, et al., EphB receptor tyrosine kinases control morphological development of the ventral midbrain. Mech Dev. 2005 Apr;122(4):501-12
Assay type: RNA in situ
MGI Accession ID: MGI:5616096
Gene symbol: Ephb2
Gene name: Eph receptor B2
Probe: EphB2 cDNA4
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Regionally restricted 2A Expression limited to ventral forebrain and ventral midbrain.
TS17: midbrain Present Regionally restricted 2A Expression limited to ventral forebrain and ventral midbrain.
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Weak Regionally restricted Authors report expression pattern was the same as for E10.5 embryos but much fainter.
TS15: future midbrain Weak Regionally restricted Authors report expression pattern was the same as for E10.5 embryos but much fainter.
Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 2C Expression in ventral midbrain, encompassing the ventral midline and extending laterally.
Specimen 2D: embryonic day 10.5 (more )
Note: Double labeled: blue - Ephb2; yellow - Isl1 (assay MGI:5616100).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 2D Expression in ventral midbrain, encompassing the ventral midline and extending laterally, limited to neuroepithelial cells. No expression in nIII motor neuron clusters.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory