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Gene Expression Data
Assay Details
Assay
Reference: J:202263 Jolly LA, et al., The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth. Hum Mol Genet. 2013 Dec 1;22(23):4673-87
Assay type: RNA in situ
MGI Accession ID: MGI:5615948
Gene symbol: Upf3b
Gene name: UPF3 regulator of nonsense transcripts homolog B (yeast)
Probe: Upf3b probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Two probes were described MGI:5615753 and MGI:5615754. Either may have been used in this assay.
Results
Specimen 1Ai: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 1A Upf3b i
Specimen S2 E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Widespread S2_Upf3b E10.5
TS17: central nervous system Strong Widespread S2_Upf3b E10.5
Specimen S2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain ventricular layer Present S2_Upf3b E14.5
Specimen S2 E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forebrain ventricular layer Present S2_Upf3b E18.5
TS26: cortical plate Present S2_Upf3b E18.5 Expression was in neurons.
TS26: hippocampus Present Regionally restricted S2_Upf3b E18.5 Expression was in the stratum pyramidale.
TS26: dentate gyrus Present S2_Upf3b E18.5
TS26: cerebellum Present Regionally restricted S2_Upf3b E18.5 Expression was detected in the granule cell progenitors within the external germinal layer.
Specimen S2 P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: neocortex layer Present S2_Upf3b P2 Expression was in neurons.
TS27: cerebellum external granule cell layer Present S2_Upf3b P2
TS27: dentate gyrus Present S2_Upf3b P2
TS27: hippocampus pyramidal cell layer Present S2_Upf3b P2
Specimen S2 P8: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present S2_Upf3b P8 Expression was in neurons.
TS28: cerebellum external granule cell layer Present S2_Upf3b P8
TS28: dentate gyrus Present S2_Upf3b P8
TS28: hippocampus pyramidal cell layer Present S2_Upf3b P8
Specimen S2 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present S2_Upf3b Adult Expression was in neurons.
TS28: dentate gyrus Present S2_Upf3b Adult
TS28: hippocampus pyramidal cell layer Present S2_Upf3b Adult
TS28: cerebellum external granule cell layer Present S2_Upf3b Adult Expression was in neurons.
Specimen S3 Cortex: postnatal adult (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present S3_Upf3b Cortex
Specimen S3 Hippocampus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present S3_Upf3b Hippocampus
TS28: hippocampus pyramidal cell layer Present S3_Upf3b Hippocampus
Specimen S4 P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Present S4_Upf3b P2
Specimen S4 P8: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S4_Upf3b P8
Specimen S4 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S4_Upf3b Adult Expression was in neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory